CALL FOR PAPERS Physiological Genomics of Exercise in Health and Disease Identification of human exercise-induced myokines using secretome analysis
نویسندگان
چکیده
Milène Catoire, Marco Mensink, Eric Kalkhoven, Patrick Schrauwen, and Sander Kersten Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen University, Wageningen, the Netherlands; Department of Metabolic Diseases, University Medical Centre Utrecht, Utrecht, the Netherlands; and Department of Human Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
منابع مشابه
Identification of human exercise-induced myokines using secretome analysis.
Endurance exercise is associated with significant improvements in cardio-metabolic risk parameters. A role for myokines has been hypothesized, yet limited information is available about myokines induced by acute endurance exercise in humans. Therefore, the aim of the study was to identify novel exercise-induced myokines in humans. To this end, we carried out a 1 h one-legged acute endurance exe...
متن کاملA role for maternally derived myokines to optimize placental function and fetal growth across gestation.
Exercise during pregnancy is associated with improved health outcomes for both mother and baby, including a reduced risk of future obesity and susceptibility to chronic diseases. Overwhelming evidence demonstrates a protective effect of maternal exercise against fetal birth weight extremes, reducing the rates of both large- and small-for-gestational-age infants. It is speculated that this prote...
متن کاملYour Call Could not be Completed as Dialled: Why Truth Does not Speak to Power In Global Health; Comment on “Knowledge, Moral Claims and the Exercise of Power in Global Health”
This article contends that legitimacy in the exercise of power comes from the consent of those subject to it. In global health, this implies that the participation of poor country citizens is required for the legitimacy of major actors and institutions. But a review of institutions and processes suggests that this participation is limited or absent. Particularly because of the complex political...
متن کاملIdentification and Validation of Novel Contraction-Regulated Myokines Released from Primary Human Skeletal Muscle Cells
Proteins secreted by skeletal muscle, so called myokines, have been shown to affect muscle physiology and additionally exert systemic effects on other tissues and organs. Although recent profiling studies have identified numerous myokines, the amount of overlap from these studies indicates that the secretome of skeletal muscle is still incompletely characterized. One limitation of the models us...
متن کاملThe Potential Role of Contraction-Induced Myokines in the Regulation of Metabolic Function for the Prevention and Treatment of Type 2 Diabetes
Skeletal muscle represents the largest organ in the body, comprises 36-42% of body weight, and has recently been recognized as having an endocrine function. Proteins expressed and released by muscle that have autocrine, paracrine, and endocrine bioactivities have been termed myokines. It is likely that muscle contraction represents the primary stimulus for the synthesis and secretion of myokine...
متن کامل